Health and Nutrition
Harvard Study Finds Oranges May Cut Depression Risk by 20%
Research links daily citrus intake to improved gut health and mood regulation through key neurotransmitters
- Yitzhak Eitan
- פורסם י"ב אדר התשפ"ה

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A study published in the scientific journal Microbiome reveals that eating oranges and other citrus fruits may significantly lower the risk of depression. Conducted by researchers at Harvard University, the study highlights the positive impact citrus compounds have on gut bacteria, which in turn influence the balance of neurotransmitters in the brain.
The research analyzed data from over 32,000 middle-aged women who participated in a long-term study between 2003 and 2017. Researchers examined their dietary habits and compared them to self-reported symptoms of depression. The findings showed that women who ate one orange a day reduced their risk of depression by about 20% compared to women who didn’t consume citrus fruits.
The researchers identified a link between citrus fruit consumption and the growth of a beneficial gut bacterium known to support digestive health and reduce inflammation in the body. This particular bacterium may help alleviate symptoms of depression by influencing metabolic pathways involved in the production of serotonin and dopamine, which are neurotransmitters that play a key role in regulating mood.
Dr. Raaj Mehta, who led the study, noted that the effect was specific to citrus fruits. The same benefit was not observed in the consumption of other fruits such as apples or bananas. Additional studies involving men revealed a similar trend, further emphasizing the importance of a balanced diet for mental health.
While the study supports earlier findings on the connection between gut microbiome health and brain function, experts caution that more research is needed to confirm a direct causal relationship. Still, for those looking for natural ways to support emotional well-being, adding an orange to your daily routine might be a simple and effective step.